| 2024-02 |
Magneto-acoustic protein nanostructures for non-invasive imaging of tissue mechanics in vivo |
Nature Materials
|
| 2023-11 |
Association between serum high-density lipoprotein cholesterol and lung function in adults: three cross-sectional studies from US and Korea National Health and Nutrition Examination Survey |
BMJ open respiratory research
|
| 2023-11 |
Fecal microbiota transplantation improves hepatic fibro-inflammation via regulating oxidative stress in experimental NASH |
Digestive and Liver Disease
|
| 2023-08 |
FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner |
Cell Death and Disease
|
| 2022-08 |
Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model |
Gastroenterology Report
|
| 2022-06 |
A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome |
HEPATOLOGY
|
| 2022-04 |
PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway |
Redox Biology
|
| 2022-03 |
Lysosomal Ca2+-mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic β-cells to metabolic stress |
NATURE COMMUNICATIONS
|
| 2021-02 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) |
AUTOPHAGY
|
| 2020-11 |
SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity |
AUTOPHAGY
|
| 2020-10 |
Interplay between saturated free fatty acids and mmLDL induces inflammation in LPS-stimulated macrophages |
KOREAN CIRCULATION JOURNAL
|
| 2020-10 |
Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma? |
Clinical and molecular hepatology
|
| 2020-09 |
All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells |
YONSEI MEDICAL JOURNAL
|
| 2020-01 |
Ezetimibe ameliorates lipid accumulation during adipogenesis by regulating the AMPK-mTORC1 pathway |
FASEB JOURNAL
|
| 2020-01 |
Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity |
AUTOPHAGY
|
| 2019-06 |
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2019-06 |
Implantable Vascularized Liver Chip for Cross‐Validation of Disease Treatment with Animal Model |
ADVANCED FUNCTIONAL MATERIALS
|
| 2019-06 |
Repositioning of niclosamide ethanolamine (NEN), an anthelmintic drug, for the treatment of lipotoxicity |
FREE RADICAL BIOLOGY AND MEDICINE
|
| 2019-03 |
Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation |
BMB REPORTS
|
| 2018-10 |
CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes |
PLOS ONE
|
| 2018-09 |
The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition |
Frontiers in Endocrinology
|
| 2017-10 |
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated mediated activation of autophagy and NLRP3 inflammasome inhibition |
AUTOPHAGY
|
| 2017-05 |
TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway |
AUTOPHAGY
|
| 2017-02 |
The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity |
BMB REPORTS
|
| 2016-12 |
p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death |
FREE RADICAL RESEARCH
|
| 2016-10 |
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis |
FREE RADICAL BIOLOGY AND MEDICINE
|
| 2016-06 |
SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages. |
AUTOPHAGY
|
| 2015-11 |
The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1 |
FREE RADICAL BIOLOGY AND MEDICINE
|
| 2015-10 |
Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity. |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-10 |
PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1. |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-09 |
Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-09 |
p62 prevents carbonyl cyanide m-chlorophenyl hydrazine (CCCP)-induced apoptotic cell death by activating Nrf2 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2013-08 |
Study of the Signaling Function of Sulfiredoxin and Peroxiredoxin III in Isolated Adrenal Gland: Unsuitability of Clonal and Primary Adrenocortical Cells |
METHODS IN ENZYMOLOGY
|
| 2013-01 |
Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage |
CELL METABOLISM
|
| 2012-11 |
Peroxiredoxin III and Sulfiredoxin Together Protect Mice from Pyrazole-Induced Oxidative Liver Injury |
ANTIOXIDANTS & REDOX SIGNALING
|
| 2012-10 |
Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|
| 2012-06 |
Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria |
MOLECULAR CELL
|
| 2011-03 |
Concerted Action of Sulfiredoxin and Peroxiredoxin I Protects Against Alcohol-Induced Oxidative Injury in Mouse Liver |
HEPATOLOGY
|
| 2009-05 |
Induction of Sulfiredoxin via an Nrf2-Dependent Pathway and Hyperoxidation of Peroxiredoxin III in the Lungs of Mice Exposed to Hyperoxia |
Antioxidants & Redox Signaling
|
| 2009-04 |
Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins |
Antioxidants & Redox Signaling
|