| 2022-12 |
Enhanced tumor targeting and timely viral release of mesenchymal stem cells/oncolytic virus complex due to GRP78 and inducible E1B55K expressions greatly increase the antitumor effect of systemic treatment |
Molecular Therapy - Oncolytics
|
| 2021-01 |
Enhanced oncolytic adenoviral production by downregulation of death-domainassociated protein and overexpression of precursor terminal protein |
SCIENTIFIC REPORTS
|
| 2019-10 |
High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2018-12 |
TGF-β downregulation-induced cancer cell death is finely regulated by SAPKs signaling cascade |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2018-03 |
Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth |
GENOME RESEARCH
|
| 2017-09 |
Down-regulation of TGF-β expression sensitizes the resistance of hepatocellular carcinoma cells to sorafenib |
YONSEI MEDICAL JOURNAL
|
| 2017-02 |
Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation |
ONCOTARGET
|
| 2016-03 |
Survivin silencing and TRAIL expression using oncolytic adenovirus increase anti-tumorigenic activity in gemcitabine-resistant pancreatic cancer cells. |
APOPTOSIS
|
| 2015-06 |
Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viralr eplication and cellular arrest |
CELLULAR SIGNALLING
|
| 2015-04 |
Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells |
CELLULAR SIGNALLING
|
| 2014-10 |
Establishment of a mouse melanoma model system for the efficient infection and replication of human adenovirus type 5-based oncolytic virus |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2013-05 |
Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment: Inhibition of apoptosis by caspase degradation. |
CELLULAR SIGNALLING
|
| 2013-04 |
The effectiveness of the oncolytic activity induced by Ad5/F35 adenoviral vector is dependent on the cumulative cellular conditions of survival and autophagy |
INTERNATIONAL JOURNAL OF ONCOLOGY
|
| 2013-02 |
c-Cbl shRNA-expressing adenovirus sensitizes TRAIL-induced apoptosis in prostate cancer DU-145 through increases of DR4/5. |
CANCER GENE THERAPY
|
| 2013-02 |
Transforming growth factor-β gene silencing using adenovirus expressing TGF-β1 or TGF-β2 shRNA. |
CANCER GENE THERAPY
|
| 2013-01 |
TRAIL/MEKK4/p38/HSP27/Akt survival network is biphasically modulated by the Src/CIN85/c-Cbl complex |
CELLULAR SIGNALLING
|
| 2012-03 |
HSP27 modulates survival signaling networks in cells treated with curcumin and TRAIL |
CELLULAR SIGNALLING
|
| 2011-02 |
MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylation |
ONCOLOGY REPORTS
|
| 2011-01 |
TRAIL-induced caspase/p38 activation is responsible for the increased catalytic and invasive activities of Akt |
INTERNATIONAL JOURNAL OF ONCOLOGY
|
| 2010-03 |
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment |
Cellular Signalling
|
| 2010-03 |
c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance |
Cellular Signalling
|
| 2008-05 |
Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily |
Cellular Signalling
|
| 2007-03 |
Differential activation of the JNK signal pathway by UV irradiation and glucose deprivation |
CELLULAR SIGNALLING
|
| 2007-01 |
Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance - Involvement of Bcl-xL |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2005-12 |
Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2005-11 |
Signal pathway of hypoxia-inducible factor-1 alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells |
CLINICAL CANCER RESEARCH
|
| 2005-07 |
Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2005-07 |
Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: A negative feedback loop |
JOURNAL OF CELL BIOLOGY
|
| 2004-08 |
Daxx deletion mutant (amino acids 501-625)-induced apoptosis occurs through the JNK/p38-Bax-dependent mitochondrial pathway |
JOURNAL OF CELLULAR BIOCHEMISTRY
|
| 2004-07 |
Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2004-02 |
Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway |
EXPERIMENTAL CELL RESEARCH
|
| 2003-11 |
Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2003-11 |
dl-VSVG-LacZ, a VSV-G epitope incorporated adenoviurs exhibit marked enhancement in gene transduction efficiency |
HUMAN GENE THERAPY
|
| 2003-10 |
Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: Hydrogen peroxide as a major second messenger of metabolic oxidative stress |
JOURNAL OF CELLULAR BIOCHEMISTRY
|
| 2003-08 |
Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1 |
BIOCHEMICAL JOURNAL
|
| 2003-08 |
Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt |
EXPERIMENTAL CELL RESEARCH
|
| 2003-07 |
Effect of glucose concentration on activation of the ASK1-SEK1-JNK1 signal transduction pathway |
JOURNAL OF CELLULAR BIOCHEMISTRY
|
| 2003-05 |
Optimization of vesicular stomatitis virus-G pseudotyped feline immunodeficiency virus vector for minimized cytotoxicity with efficient gene transfer |
VIRUS RESEARCH
|
| 2002-12 |
Enhancement of metabolic oxidative stress-induced cytotoxicity by the thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide is mediated through the ASK1-SEK1-JNK1 pathway |
MOLECULAR PHARMACOLOGY
|
| 2002-11 |
Role of glutaredoxin in metabolic oxidative stress - Glutaredoxin as a sensor of oxidative stress mediated by H2O2 |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2001-01 |
Efficient gene transfer of VSV-G pseudotyped retroviral vector to human brain tumor |
GENE THERAPY
|
| 2000-01 |
Transduction effect of antisense K-ras on malignant phenotypes in gastric cancer cells |
CANCER LETTERS
|