| 2024-03 |
CRISPR/Cas9 targeting of passenger single nucleotide variants in haploinsufficient or essential genes expands cancer therapy prospects |
Scientific Reports
|
| 2023-09 |
Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy |
Theranostics
|
| 2022-12 |
Selective cytotoxicity of a novel mitochondrial complex I inhibitor, YK-135, against EMT-subtype gastric cancer cell lines due to impaired glycolytic capacity |
BMB Reports
|
| 2022-11 |
WNK3 inhibition elicits antitumor immunity by suppressing PD-L1 expression on tumor cells and activating T-cell function |
Experimental and Molecular Medicine
|
| 2022-08 |
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells |
CANCER COMMUNICATIONS
|
| 2022-04 |
Gold(I)-Catalyzed Intramolecular Hydrothiophenylation of N-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2- b]pyridine-5(4 H)-ones: Development of F-Actin Specific Fluorescent Probes |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2022-02 |
Establishment of reference standards for multifaceted mosaic variant analysis |
Scientific Data
|
| 2021-08 |
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling |
SCIENTIFIC REPORTS
|
| 2020-07 |
Cross-species oncogenic signatures of breast cancer in canine mammary tumors |
NATURE COMMUNICATIONS
|
| 2020-07 |
Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities |
NATURE COMMUNICATIONS
|
| 2020-05 |
Pharmacogenomic analysis reveals CCNA2 as a predictive biomarker of sensitivity to polo-like kinase i inhibitor in gastric cancer |
Cancers
|
| 2019-10 |
A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery |
Cell Chemical Biology
|
| 2019-10 |
Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3’ trailer-derived tRNA fragments |
NUCLEIC ACIDS RESEARCH
|
| 2018-09 |
Selective Cytotoxicity of the NAMPT Inhibitor FK866 Toward Gastric Cancer Cells with Markers of the Epithelial–Mesenchymal Transition, Due to Loss of NAPRT |
GASTROENTEROLOGY
|
| 2018-05 |
Chemistry-first approach for nomination of personalized treatment in lung cancer |
CELL
|
| 2018-02 |
A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells |
SCIENTIFIC REPORTS
|
| 2017-12 |
Somatic mutation driven codon transition bias in human cancer |
SCIENTIFIC REPORTS
|
| 2017-06 |
Identification of Pharmacologically Tractable Protein Complexes in Cancer Using the R-Based Network Clustering and Visualization Program MCODER |
BIOMED RESEARCH INTERNATIONAL
|
| 2016-10 |
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer |
NATURE
|
| 2016-10 |
Emerging power of proteomics for delineation of intrinsic tumor subtypes and resistance mechanisms to anti-cancer therapies |
EXPERT REVIEW OF PROTEOMICS
|
| 2016-09 |
KSR1 and EPHB4 Regulate Myc and PGC1beta To Promote Survival of Human Colon Tumors |
MOLECULAR AND CELLULAR BIOLOGY
|
| 2016-05 |
Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer |
BIOINFORMATICS
|
| 2016-01 |
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker |
CANCER PREVENTION RESEARCH
|
| 2015-12 |
A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression |
MOLECULAR SYSTEMS BIOLOGY
|
| 2015-11 |
AMPK Promotes Aberrant PGC1-beta Expression To Support Human Colon Tumor Cell Survival |
MOLECULAR AND CELLULAR BIOLOGY
|
| 2015-09 |
Meta-analysis of large-scale toxicogenomic data finds neuronal regeneration related protein and cathepsin D to be novel biomarkers of drug-induced toxicity |
PLOS ONE
|
| 2015-08 |
Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer Medicine |
YONSEI MEDICAL JOURNAL
|
| 2015-06 |
Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B |
NATURE CHEMICAL BIOLOGY
|
| 2014-06 |
Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens |
NUCLEIC ACIDS RESEARCH
|
| 2013-10 |
Using Functional Signature Ontology (FUSION) to Identify Mechanisms of Action for Natural Products |
SCIENCE SIGNALING
|
| 2013-10 |
Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer |
CELL
|
| 2013-03 |
siMacro: A Fast and Easy Data Processing Tool for Cell-Based Genomewide siRNA Screens |
Genomics & Informatics
|
| 2013-01 |
GWAS Meets TCGA to Illuminate Mechanisms of Cancer Predisposition |
CELL
|
| 2012-08 |
Host Modulators of H1N1 Cytopathogenicity |
PLOS ONE
|
| 2012-07 |
A Noncomplementation Screen for Quantitative Trait Alleles in Saccharomyces cerevisiae |
G3-GENES GENOMES GENETICS
|
| 2007-12 |
Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
|